Oxidized lipids and lipoproteins in patients with stroke: A pilot study

Abstract

The objective of this pilot study was to investigate the status of oxidized lipid in Iraqi stroke patients. Blood samples were collected from subjects diagnosed with stroke and blood lipids and oxidized lipoprotein were analyzed using enzymatic and colorimetric methods. We found a significant (p < 0.001) increase in total lipids, and total lipid oxidation as measured by serum aldehyde malondialdehyde. We also found a significant increase in level of oxidized low density lipoproteins in patient with stroke in comparison with healthy individuals. In conclusion, our finding supports the use of oxidized LDL as a marker of stroke.

Keywords: Blood, colorimetric methods, malondialdehyde, ischemic stroke, cholesterol.